In 1995 John Medeiros and his identical twin brother participated in a gene therapy study in which the HIV-positive twin was infused with billions of genes from the HIV-negative twin. This memoir details, from a firsthand perspective, a time in our recent history when the world had to reckon with the emergence of a seemingly undefeatable virus. SELF, DIVIDED explores the dysfunctional yet enduring relationships that surround this pivotal moment in Medeiros's life and family, brilliantly capturing how we all are connected, in one way or another, to those around us.