Before the events of the 2021 animated series, Resident Evil: Infinite Darkness, Leon Kennedy is called in to investigate alongside Pittsburgh PD when a bomb kills a guard at the Carnegie Museum of Art. But when that guard rises from the autopsy table and begins a chain reaction of undead corpses hunting for blood, Leon is once again caught in a complex web of intrigue. A terrorist cult, a mysterious virus, and the corpses of the dead returning to life to assault the living...

"How a story is portrayed is as important as what it portrays. And here is where this graphic novel shines. The pacing is perfect, the artwork is as gritty as the story and that’s a good thing. The humanity of it all, the little nuances that are usually overlooked with human emotions in works of fiction are easy to pick up and that’s not only commendable, it’s worthy of praise. Overall Resident Evil Infinite Darkness: The Beginning is a welcomed addition to the franchise." — JP Kristov, Anime Corner