"Life's Greatest Secret is the logical sequel to Jim Watson's The Double Helix. While Watson and Crick deserve their plaudits for discovering the structure of DNA, that was only part of the story. Beginning to understand how that helix works--how its DNA code is turned into bodies and behaviors--took another 15 years of amazing work by an army of dedicated men and women. These are the unknown heroes of modern genetics, and their tale is the subject of Cobb's fascinating book. Every now and again I had to stop reading because the amazement overload was too great."--Jerry Coyne, professor of ecology and evolution, the University of Chicago, and author of Why Evolution Is True
"[A] fine history of genetics.... [A] gripping, insightful history, often from the mouths of the participants themselves."--Kirkus Reviews (starred)
"[A] masterly account.... Cobb's book is a delight. Even those who know parts of the story quite well will find fresh, intriguing vignettes."--Guardian
"[T]he cracking of the code of life is a great story, of which this is an accomplished telling."--Economist
"A lucid explanation of the science and the stories of key players."--Nature
"An authoritative but nevertheless thrilling narrative.... In short, this is a first-class read."--Observer
"Cobb covers well-plowed ground, but he does so in a manner both thoroughly engaging and truly edifying."--Publishers Weekly
"Like Cobb's other titles, this scholarly work reflects extensive research and draws upon primary documents. Upper-level students and researchers in biology or the history of science are best equipped to appreciate this detailed book."--Library Journal
"Matthew Cobb is a respected scientist and historian, and he has combined both disciplines to spectacular effect in this wonderful book. A compelling, authoritative, and insightful account of how life works at the deepest level. Bloody brilliant!"--Brian Cox, professor of physics, the University of Manchester and author of Why Does E=mc²?
"Most people think the race to sequence the human genome culminated at the 2000 White House 'Mission Accomplished' announcement. In Matthew Cobb's Life's Greatest Secret, we learn that it was just one chapter of a far more interesting and continuing story."--Eric Topol, professor of genomics and director, Scripps Translational Science Institute, and author of The Patient Will See You Now
"Readers of Mr. Cobb's book will learn much about the history and current state of modern biology."--Wall Street Journal
"The third of the grand unifying theories of biology was completed in the 20th Century, following Darwin's evolution by natural selection, and Cell Theory a century earlier. DNA, the double helix, and the universality of the genetic code radically transformed our understanding of life: no area in biology has been untouched by this revolution, from cancer to human origins to genetic engineering, and now, to the future of data storage. Cobb, a scientist and thorough historian, is a master storyteller, and recounts the thrilling science, politics, egos of this grand scientific revolution. Essential, definitive reading."--Adam Rutherford, author of Creation: How Science Is Reinventing Life Itself