A lament for the death of print media, the growth of the corporation, and the process of growing old, Juice! serves as a tragi-comedy chronicling the increased anxieties of "post-race" America.

In 2010, the Newseum in Washington D.C. finally obtained the suit O. J. Simpson wore in court the day he was acquitted, and it now stands as both an artifact in their "Trial of the Century" exhibit and as a symbol of the American media's endless hunger for the criminal and the celebrity. This event serves as a launching point for Ishmael Reed's "Juice!," a novelistic commentary on the post-Simpson American media frenzy from one of the most controversial figures in American literature today. Through the figure Paul Blessings--a censored cartoonist suffering from diabetes--and his cohorts--serving as stand-ins for the various mediums of art--Ishmael Reed argues that since 1994, "O. J. has become a metaphor for things wrong with culture and politics."