Jack Jetstark travels the universe to seek out the descendants of superpowered freaks created long ago by VesCorp scientists. The vibrations encoded in a particular song transform the members of Jack's crew into a firebreather and an angel, a wildman and telepathic conjoined triplets, so they hide the truth of who they really are with the theatrics of a carnival.

The song plays every night through the receptor Jack carries with them, but when one night it has a different ending and their temporary powers become permanent, Jack believes the change is a signal from the woman who sent him on this quest in the first place. He and his freaks must navigate a universe at war to protect the love of his life.

But does the ruler of VesCorp really need protecting?