X in Sex: How the X Chromosome Controls Our Lives


Product Details

Harvard University Press
Publish Date
5.48 X 8.24 X 0.61 inches | 0.01 pounds

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About the Author

David A. Bainbridge first worked on community design, passive solar heating and cooling, building codes, and solar rights at the innovative design firm Living Systems. He described his first water-wall solar home and the Village Homes solar subdivision in Solar House Designs in 1978. Founder of the Passive Solar Institute, and recipient of the ASES Passive Pioneer Award in 2004, Bainbridge consults on a wide range of residential and commercial projects and has completed several solar projects on his own homes, as well as co-authoring The Straw Bale House (with Athena Swentzell Steen and Bill Steen), and Passive Solar Architecture (with Ken Haggard). He is currently Associate Professor of Sustainable Management at the Marshall Goldsmith School of Management. He lives in San Diego, California.


In his structure/function analysis of the X chromosome, Bainbridge provides a tongue-in-cheek, yet informative, description of one of the two human sex chromosomes.--R. Adler"Choice" (09/01/2003)
The X in Sex is absolutely fascinating, so intriguing, in fact, that I found myself unwilling to put it down. David Bainbridge surveys an astonishing amount of new information from recent genomic studies of the X chromosome, clearly explaining the findings in a way the average person can easily follow. The science is presented via amusing and highly appropriate metaphors and clever turns of phrase, all of which serve to brighten the prose and present the reader with catchy ways to think about complex ideas. This is an informative, authoritative, and thoroughly enjoyable read: one of the best books I have read in recent years.--Jane Lancaster, University of New Mexico
This is wonderful stuff--beautifully written, clear, jargon-free, with anecdotes sure to hold the attention.--Tim Birkhead, author of Promiscuity: An Evolutionary History of Sperm Competition
A well-written, well-researched, easy-to-read study that explains what has been learned about the X and Y chromosomes using DNA sequencing and other molecular biology techniques. British biologist Bainbridge...has pulled together historical and current scientific research about how the X and Y chromosomes affect us and what the genes on these chromosomes actually do, like causing sex-linked diseases and color blindness...An excellent example of good science writing...Recommended.-- (03/15/2003)
There are many literary stars (such as Stephen Jay Gould, Richard Dawkins and Matt Ridley) in the firmament of writers on evolution, and to a man they write with dash and persuasive logic. David Bainbridge is one such and in his latest book he takes the reader through the glories of the X chromosome at a cracking pace.-- (04/25/2003)
The truth is that the behaviours of [chromosomes] X and Y are inextricably linked. Bainbridge explores this link in a compelling tale that takes in how the sex chromosomes became sex chromosomes, and the very different consequences of this for women and men. Along the way we encounter the Duke of Kent's testicles, calico cats and non-identical identical twin girls. His story weaves science, history and the history of science (with a little religion for good measure) in a straightforward, anecdotal fashion that will appeal to scientists and non-scientists alike.-- (06/28/2003)
If you have ever been intrigued by some of the puzzles of genetics--why boys tend to get haemophilia or colour blindness while girls are more likely to have an identical twin or to develop rheumatoid arthritis later in life--then The X in Sex is for you.-- (10/24/2003)
David Bainbridge's The X in Sex prove[s] that popular books on human genetics--indeed on human sex chromosomes--need not trade in sociobiological excess...He spends much of his time on 'sex-linked' conditions that affect men more than women; these range from annoyances like baldness to devastating diseases like muscular dystrophy. Bainbridge also devotes many fascinating pages to complex ailments like autoimmune disease that, for reasons which remain unclear, disproportionately afflict women...But Bainbridge's chief concern is with the biology of human sex determination and with the many ways in which it can, and does, go wrong. In the end, his message is that while human beings obviously come in two predominant sexes, both cultural and biological forces give rise to a surprisingly 'continuous spectrum of gender.'-- (05/12/2005)
David Bainbridge takes us on a fascinating tour of X chromosomes and explains what the possession of these intricately folded, infinitessimally narrow, two-inch long strings of genetic codes weighing almost nothing, means for their bearers--that is for each one of us, male and female. History and personal anecdotes are woven together with up-to-date summaries of the science, punctuated with Bainbridge's zany--and very British--humor, so that this information-packed book is pure pleasure to read.--Sarah Blaffer Hrdy author of Mother Nature: A History of Mothers, Infants, and Natural Selection
Bainbridge is an essentialist, interested in understanding what aspects of gender are biologically driven, and why...He has a central question he wants to answer. The question is not so much why men and women are different (a worn topic that's the subject of too many Mars-and-Venus bestsellers) but, far more specific and far more interesting: Why are men and women more different than they need to be?-- (03/23/2003)
Bainbridge summarizes our knowledge of the genetic information that determines one's sex by recounting the ancients' speculations about the genesis of gender, following with modern biologists' discovery of the X and Y chromosomes about a century ago, and of the sex-determining gene Sry in the 1990s. In a discussion rich with history, evolution, and philosophy, Bainbridge points out the dramatic effect that gender selection has on people's lives...A fascinating, often humorous analysis of the science of sexuality.-- (02/01/2003)
In The X in Sex, David Bainbridge explains the far-reaching effects of X. Bainbridge...moves with ease between straightforward accounts of biology and historical stories about its effect, like the chapter describing the progression of hemophilia through the royal houses of Europe. Bainbridge discusses cultural history as well as natural history, and his wit enlivens every page.-- (04/13/2003)
The author of Making Babies takes a lively, witty tour of the X chromosome, creator of "a delicious symmetry between men and women"...Entertaining and informative...A fine demonstration of science made accessible.-- (12/01/2002)
This highly readable book tells the story of the X chromosome from Aristotle's musings on gender differences right through to a modern understanding of the genetics of the X chromosome. The author's engaging style makes modern genetics accessible both of the complete layperson and to those of us for whom preclinical genetics are a hazy memory...In a chapter entitled "The Duke of Kent's Testicles", Bainbridge describes the unfortunate spread of haemophilia (sic) through19th century European Royal families to illustrate the inheritance of sex-linked disorders. From a disastrous random mutation in a sperm in one of the Duke's testicles to the Russian Revolution, the history is irreverent but the genetic implications are well illustrated...This slim book is a good read, amusing yet informative and authoritative.--Alex Connan "Journal of Family Planning and Reproductive Heath Care "